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Accelerated TMS Treatment for Depression
TMS does not have to look the same for every patient.
At New Chapter TMS, we offer three treatment paths. Our 1-Week Accelerated and One-D Protocols are available only when depression is the primary diagnosis. For OCD and other conditions, we recommend Standard TMS, one treatment per day. For depression, the right path depends on your history, schedule, goals, and clinical situation:
Three TMS Options at New Chapter
Standard TMS
This is the traditional TMS schedule: one treatment per day, usually Monday through Friday, over several weeks.
Standard TMS is often a strong fit for patients who:
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want the most established and widely studied treatment structure [1]
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prefer a steadier pace
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schedule is better fit for regular weekday visits
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are being treated for OCD or another condition other than depression (Standard TMS is our recommended format)
1-Week Accelerated
For patients whose primary diagnosis is depression, our 1-Week Accelerated option compresses a full standard course of TMS into one week by delivering multiple treatments per day.
This approach follows the growing literature on accelerated TMS and the pragmatic model described by Luehr et al.[2] taking the familiar 36-treatment course and delivering it in a shorter timeframe. At New Chapter, we use FDA-cleared standard 20-minute treatments in this accelerated format.
This may be a good fit for patients who:
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have depression as their primary diagnosis
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want a faster treatment timeline
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cannot realistically attend 6–8 weeks of daily visits
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are traveling for treatment
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want an evidence-informed accelerated option
1-Day Protocol
For patients whose primary diagnosis is depression, our One-D Protocol is our most compressed treatment option, delivering 20 treatments in a single day.
This approach is based on emerging accelerated-TMS research associated with Jonathan Downar MD and colleagues [3]. It is designed for carefully selected patients after a thorough clinical evaluation.
This may be a good fit for patients who:
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have depression as their primary diagnosis
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are seeking the most time-efficient option
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are traveling from farther away
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want to explore an ultra-compressed treatment schedule
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understand this is a more specialized pathway
How the Options Compare
Standard TMS - 6–8 weeks
1-Week Accelerated - 5 days
One-D Protocol - 1 day
Three different timelines. One shared goal: helping you move toward relief. Accelerated timelines apply to depression treatment only.
Which Option Is Best?
There is no one “best” protocol for everyone.
The right fit depends on:
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your primary diagnosis (accelerated options are for depression only)
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your depression history
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prior treatment response
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how quickly you want to move forward
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your schedule and life demands
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insurance and financial considerations
For some patients, standard TMS is the best place to start.
For others, an accelerated option may make treatment more realistic and accessible.
Why Patients Choose New Chapter for Accelerated TMS
We believe patients deserve both innovation and clarity.
That means:
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we explain options in plain language
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we do not use confusing labels as shortcuts
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we offer accelerated care grounded in published research
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we help patients compare options in a practical, non-overwhelming way
Our clinic has also been involved in formal research extending accelerated TMS protocols to teens, building on an evidence base that has historically focused on adults.
Sources
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Blumberger DM, Vila-Rodriguez F, Thorpe KE, et al. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomized non-inferiority trial. The Lancet. 2018;391(10131):1683-1692.
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Luehr J, et al. Pragmatic accelerated transcranial magnetic stimulation: delivering 36 treatments in 5 days. 2024.
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Downar J, et al. Accelerated transcranial magnetic stimulation delivered in a single day (ONE-D protocol): case series and emerging evidence. 2025.
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Cole EJ, Stimpson KH, Bentzley BS, et al. Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression (SAINT). American Journal of Psychiatry. 2020;177(8):716-726.
